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A cost-effectiveness analysis of two different antimicrobial stewardship programs BJID
Okumura,Lucas Miyake; Riveros,Bruno Salgado; Gomes-da-Silva,Monica Maria; Veroneze,Izelandia.
Abstract There is a lack of formal economic analysis to assess the efficiency of antimicrobial stewardship programs. Herein, we conducted a cost-effectiveness study to assess two different strategies of Antimicrobial Stewardship Programs. A 30-day Markov model was developed to analyze how cost-effective was a Bundled Antimicrobial Stewardship implemented in a university hospital in Brazil. Clinical data derived from a historical cohort that compared two different strategies of antimicrobial stewardship programs and had 30-day mortality as main outcome. Selected costs included: workload, cost of defined daily doses, length of stay, laboratory and imaging resources used to diagnose infections. Data were analyzed by deterministic and probabilistic sensitivity...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antimicrobial stewardship program; Cost-effectiveness; Mortality; Pharmacist.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000300006
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Impact of piperacillin-tazobactam shortage on meropenem use: implications for antimicrobial stewardship programs BJID
Barber,Katie E.; Bell,Allison M.; King,S. Travis; Parham,Jason J.; Stover,Kayla R..
ABSTRACT Drug shortages pose a clear detriment to antimicrobial stewardship (AS) efforts. Our objective was to evaluate the effect of a piperacillin-tazobactam shortage on meropenem use, related costs, and associated changes in AS activity. A quasi-experimental quality improvement review compared adult patients receiving meropenem ≥72 h three months pre-shortage and three months during the shortage. 320 patients were included (pre-shortage: 103; shortage: 217). Baseline characteristics were similar, but the length of stay was slightly longer in pre-shortage [19 (11-32) days] versus shortage [16 (11-32) days] (p = 0.094). In pre-shortage and shortage, median days of therapy and estimated meropenem cost were 7 (5-11) and 7 (5-10) and $309.93...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Piperacillin; Meropenem; Pharmaceutical; Antimicrobial stewardship program.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600631
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